Let me preface this by saying that I am familiar with Rabbi Sacks. A learned Hebraic scholar, he speaks with authority on Jewish history and law, the Torah, and midrash. That said, he is still a believer, still a superstitionalist, still a rejecter of reality.
I reject his basic premise of the need for humans to seek “meaning” outside the “system.” His examples are fraught with all kinds of problems, but hey... it’s what theists do. But I would not interpret his closing comment as a condemnation of atheists as "non-human." What he is saying is that in his opinion those who do not embrace a meaning of life beyond the "system" of nature and the reality of the natural universe, lack a trait /a belief (what Dawkin's calls "the religion meme") which is unique to humans.Now, in the rabbi’s opinion this is a defect and is a diminishing of humanity / “less than human”. But to realists, to those unencumbered by this missing "meme," or who have the ability to suppress it and over come it, substituting reason in its stead - it is an evolutionary advancement.